ISSN: 0034-8376
eISSN: 2564-8896



Letter to the Editor



I. De Boer, Department of Neurology, Leiden University Medical Center, Leiden, Netherlands
A.M.J.M. Van den Maagdenberg, Departments of Neurology and Human Genetics, Leiden University Medical Center, Leiden, Netherlands
G.M. Terwindt, Department of Neurology, Leiden University Medical Center, Leiden, Netherlands
Nancy Monroy-Jaramillo, Department of Neurogenetics, Instituto Nacional de Neurología y Neurocirugía Manuel Velasco Suárez, Mexico City, Mexico
Aurelio Cerón, Department of Neurology, Instituto Nacional de Neurología y Neurocirugía Manuel Velasco Suárez, Mexico City, Mexico
Elizabeth C√≥rdoba-Lan√ļs, Research Unit, Hospital Universitario N¬™ S¬™ de Candelaria, Santa Cruz de Tenerife, Spain
Verónica Rivas, Clinical Laboratory of Neurodegenerative Diseases, Instituto Nacional de Neurología y Neurocirugía Manuel Velasco Suárez, Mexico City, Mexico
Adriana Ochoa-Morales, Department of Neurogenetics, Instituto Nacional de Neurología y Neurocirugía Manuel Velasco Suárez, Mexico City, Mexico
María Georgina Arteaga-Alcaraz, State Research Coordination, Mexican Social Security Institute (IMSS), Pachuca, Hgo., Mexico
Fausto Carlos Nocedal-Rustrian, Hospital Regional #25 Ignacio Zaragoza, Mexican Social Security Institute, Mexico City, Mexico
Cecilia Gallegos, Department of Pathology, Hospital √Āngeles del Pedregal, Mexico City, Mexico
María Elisa Alonso-Vilatela, Department of Neurogenetics, Instituto Nacional de Neurología y Neurocirugía Manuel Velasco Suárez, Mexico City, Mexico
Teresa Corona, Clinical Neurodegenerative Disease Research Unit, Instituto Nacional de Neurología y Neurocirugía, México, D.F., México
José Flores, Clinical Laboratory of Neurodegenerative Diseases, Instituto Nacional de Neurología y Neurocirugía Manuel Velasco Suárez, Mexico City, Mexico


Dear Editor,
Recently, Monroy-Jaramillo et al. described a new family with a disorder now known as retinal vasculopathy with cerebral leukoencephalopathy and systemic manifestations (RVCL-S)2. RVCL-S is a monogenetic small vessel disease caused by C-terminal frameshift mutations in TREX1.



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